Overview

IDAllelesLocationGenome BuildSource
rs1050976C/Tchr6: 40807938dbsnp146
rs1050976C/T chr6: 408079 37dbsnp146_grch37
imm_6_353079A/G chr6: 408079 38ImmunoChip
imm_6_353079A/G chr6: 408079 37ImmunoChip
imm_6_353079A/G chr6: 353079 36ImmunoChip

Jbrowse

Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs386513980rs1050976rs1050976142
rs17839859rs1050976rs1050976123
rs3191341rs1050976rs1050976106
rs17234139rs1050976rs1050976123

Criteria

rs1050976 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs1050976 as derived from dbSNP:
  • in 3prime utr
Gene(s) at location of variation:  IRF4 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs1050976, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.