Overview

IDAllelesLocationGenome BuildSource
rs2187668C/Tchr6: 3263810738dbsnp146
rs2187668C/T chr6: 32605884 37dbsnp146_grch37
rs2187668T/C chr6: 32638107 38ImmunoChip
rs2187668T/C chr6: 32605884 37ImmunoChip
rs2187668T/C chr6: 32713862 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs36182703rs2187668rs2187668130
rs111767434rs77691257rs2187668135
rs35922537rs2187668rs2187668127
rs77691257rs2187668rs2187668136
rs386499469rs2187668rs2187668142
rs3948779rs2187668rs2187668110
rs57194924rs2187668rs2187668130
rs9272481rs2187668rs2187668123
rs56581219rs2187668rs2187668130
rs74942078rs2187668rs2187668137

Criteria

rs2187668 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 
Marker is in r2>0.8 with an index SNP 

Functional Information

Gene function properties for rs2187668 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  HLA-DQA1 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs2187668, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.